DST-backed Institute of Advanced Study in Science and Technology (IASST) develops ghee-based biosurfactant with antibacterial action

Key facts

• The Institute of Advanced Study in Science and Technology (IASST), an institute under the Department of Science and Technology (DST), synthesised a lipopeptide biosurfactant using probiotic Lactobacillus plantarum JBC5.
• Ghee served as the lipid substrate for biosurfactant production, and optimisation employed response surface statistical analysis.
• The biosurfactant achieved a maximum emulsification index of 60% for edible oils and reduced surface tension comparably to conventional surfactants.
• It retained thermal stability up to 276°C and remained stable across a wide pH range.
• Laboratory tests showed effectiveness against Staphylococcus aureus, a pathogen linked to skin infections and wound complications.
• When blended with commercial face washes, the compound improved stain-removal efficiency.
• Researchers are conducting toxicity assessments, dose standardisation studies, and industry collaborations to advance commercialisation.