Omicron RF.5 Sub-Variant Detected in Andhra Pradesh

Key facts

• The Omicron RF.5 sub-variant was detected in four COVID-19-positive samples from Kadapa district, Andhra Pradesh, following genome sequencing at a Pune virology laboratory.
• Andhra Pradesh Health Minister Satya Kumar Yadav confirmed the detection and reviewed the state's COVID-19 preparedness.
• The state has reported 16 COVID-19 cases so far, with hospitals equipped with special wards, beds, and testing kits.
• Director of Medical Education Vishnuvardhan stated that RF.5 is under routine genomic surveillance and the World Health Organisation (WHO) is tracking the strain.
• Current evidence indicates that RF.5 is not more dangerous than other Omicron variants and causes mild to moderate respiratory symptoms.
• RF.5 is a recombinant Omicron sub-lineage formed through genetic mixing of two related SARS-CoV-2 lineages.
• Vaccines remain critical for reducing severe illness, though they may not prevent infection completely.